A1131

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A1131

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L-Anserine nitrate salt

Synonym:β-Ala-3-methyl-His nitrate salt, β-Alanyl-3-methyl-L-histidine nitrate salt
CAS Number:10030-52-1
Linear Formula:C10H16N4O3 · HNO3
Molecular Weight:303.27
EC Number:233-079-7
MDL number:MFCD00037001
PubChem Substance ID:24890509

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Description

Biochem/physiol ActionsL-Anserine s a dipeptide found in most animal tissues. In model systems it is a potent antioxidant and scavener of hydroxyl radicals. It inhibits nonenzymatic protein glycation induced by aldose and ketose reducing sugars. It is much less potent than L-carnosine as an inhibitor of protein-protein crosslinking.
LinkageAnserine is a naturally occurring methylated analog of carnosine.

Safety

WGK Germany3

References

referenceHobart, L.J., et al., Anti-crosslinking properties of carnosine: significance of histidine. Life Sci. 75, 1379-1389, (2004)
 Szwergold, B.S., Carnosine and anserine act as effective transglycating agents in decomposition of aldose-derived Schiff bases. Biochem. Biophys. Res. Commun. 336, 36-41, (2005)
 Ukeda, H., et al., Effect of carnosine and related compounds on the inactivation of human Cu,Zn-superoxide dismutase by modification of fructose and glycolaldehyde. Biosci. Biotechnol. Biochem. 66, 36-43, (2002)
 Holliday, R., and McFarland, G.A., Inhibition of the growth of transformed and neoplastic cells by the dipeptide carnosine. Br. J. Cancer 73, 966-971, (1996)